Our lab uses a variety of techniques to study stroke in rodent models of injury. These include histology/protein expression, viral mediated gene transfer, interference RNA, transgene expression, tract tracing, chemogenetic activation, rodent behavior and wide-field calcium imaging.
Current projects
- Examining the bi-directional relationship between aging and brain injury
- Exploring the contribution of structural plasticity to long term injury, poorly localizable symptomatology, and recovery limitations after stroke.
- Molecular drivers of region-specific synaptic plasticity after experimental ischemic stroke
- Contribution of local and global changes in excitation/inhibition balance to stroke injury and recovery
- Use of EEG to examine patterns of activity which predict injury and recovery in critically ill patients with severe neurologic injury.
